4 Week Italy Tour Packages
4.5 stars on(8,092 reviews)- Choose from 7 Italy tours
- 4 verified reviews from TourRadar travelers
- 24/7 customer support
Italy itineraries for 4 weeks
Compiled by

MelissaItaly travel expert at TourRadar
23 Days in Southern Italy, incl. Rome and Sicily
A grand 23-day Italian tour takes you through 20 cities. The route features Pompeii's ancient ruins, a memorable hike on the Path of Gods along the Amalfi Coast, walks around Mount Etna's crater, and Syracuse's archaeological treasures. Comfortable hotels and guesthouses serve as bases for guided cultural tours.
- Days 1-2
Rome & Naples
Book tickets online for the Colosseum and Vatican to avoid long lines. Start your Rome visit early before the crowds build up. Take a morning train to Naples on Day 2. The journey takes about 1.5 hours. Walk through the Spanish Quarter's winding streets and make your way to Pompeii. A past visitor suggests, "Get your pizza from L'Antica Pizzeria da Michele - arrive before noon to avoid the lunch rush."
- Days 3-5
Pompeii & Sorrento Coast
Take a guided tour of Pompeii. The ancient streets are uneven, so good walking shoes are important. Start your Mt. Vesuvius climb early on Day 4 before it gets too hot. Bring plenty of water and protect yourself from the sun. Stay in Sorrento for two nights. It's perfect for visiting Capri by hydrofoil (30 minutes) and checking out local limoncello makers.
- Days 6-7
Amalfi Coast & Positano
The SITA buses will take you along the coastal road to Amalfi. Sit on the right side for the best coastal views. The Path of Gods hike from Bomerano to Positano is beautiful but start by 8 AM to beat the heat. Watch out for slippery trails after rain and wear proper hiking shoes. Take the ferry back to Minori for great views of the coastline.
- Days 8-10
Calabria Region
- Days 11-13
Tropea & Reggio Calabria
- Days 14-18
Sicily - Eastern Coast
- Days 19-23
Western Sicily & Palermo
22 Days in Italy, incl. Rome and Sicily
The 22-day Italian journey winds through 20 cities from Rome to Palermo. Marvel at UNESCO sites including Florence's Duomo and Venice's canals. Participate in hands-on cooking classes in Taormina and sample limoncello on the Amalfi Coast. Package includes 21 breakfasts and 6 authentic Italian dinners.
- Days 1-3
Rome & Florence
Your first evening in Rome is perfect for an orientation walk. Visit the Colosseum before 8:30 AM to avoid the big tour groups. Take a 3-hour train to Florence with a stop in Siena. You'll want 2-3 hours to see Siena's UNESCO-listed center. In Florence, visit the Duomo area early in the morning before the crowds arrive around 10 AM.
- Days 4-5
Tuscany & Cinque Terre
Travel west through Lucca (2 hours from Florence) and Pisa. "The less-visited back streets of Lucca were the highlight - much more authentic than tourist-heavy Pisa." Stay two nights in Cinque Terre and use the rail pass to explore the villages. Remember to check trail conditions as the hiking paths can close when it's wet.
- Days 6-8
Northern Italy
- Days 9-10
Back to Rome
- Days 11-13
Naples & Amalfi Coast
- Days 14-15
Rome to Sicily
- Days 16-19
Exploring Sicily
- Days 20-22
Palermo & Departure
22 Day Italy Itinerary, incl. Rome and Sicily
This 22-day Italian odyssey spans 21 cities from Rome to Palermo. Visit 8 UNESCO sites including Siena's center and Syracuse's ruins, plus exclusive experiences like Tuscan cooking classes and Venetian gondola rides.
- Days 1-3
Rome & Florence
Start your trip in Rome with Vatican visits at 8am to beat the crowds. After 2 nights in the Eternal City, take a 3-hour train to Florence through Siena. A recent visitor shared: "Getting into Florence early let us explore the Duomo area before the midday crush - the morning light on the baptistery doors was incredible."
- Days 4-5
Cinque Terre Region
- Days 6-8
Milan & Venice
- Days 9-11
Rome & Naples
- Days 12-14
Amalfi Coast
- Days 15-18
Eastern Sicily
- Days 19-22
Western Sicily
More about Italy
South Italy 10 day ToursSouth Italy 7 day ToursNorthern Italy 7 day ToursSicily 10 day ToursAmalfi Coast 7 day ToursAmalfi Coast 10 day ToursPuglia 10 day ToursItaly Travel Guide | All You Need to KnowItinerary Ideas for 10 Days in Italy 2025/2026Best 7 Day Italy Itineraries 2025/2026 (with Reviews)Discover the Best Italy Vacation Packages 2025/2026What is the best time to visit Italy in 2025/2026?